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AOD9604 has been studied in preclinical and early clinical settings, and it received GRAS (Generally Recognized as Safe) designation from the US FDA for use as a food ingredient

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Further surgical complications such as fixation failure, sub-optimal tunnel placement, and post-surgical issues like wound re-sutures, patella dislocation, and infection led to the exclusion of some rats from statistical analyses for gait and mechanical test data

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These can include tingling or numbness in the hands and feet